Microsoft has released Windows Defender Beta 2 (formerly Anti-Spyware) which protects your computer from spyware and other computer baddies. New features of Windows Defender include:
A redesigned and simplified user interface – Incorporating feedback from our customers, the Windows Defender UI has been redesigned to make common tasks easier to accomplish with a warning system that [...]

Winpooch is a watchdog for Windows that helps you increase the security of your computer.   Winpooch can prevent suspicious programs from doing dangerous actions such as writing to system directories or sensible registry keys. It acts as a powerful anti spyware and anti trojans, and if you have ClamWin installed, you can tell Winpooch [...]